Publications

37. Kumar R, Massoumi H, Chug MK, Brisbois EJ. S-nitroso-N-acetyl-l-cysteine ethyl ester (SNACET) catheter lock solution to reduce catheter-associated infections. ACS Applied Materials & Interfaces 2021; 13, 22, 25813–25824

36. Chug MK, Bachtiar E, Gall K, Brisbois EJ. Tailoring nitric oxide release with additive manufacturing to create antimicrobial surfaces. Biomaterials Science 2021, 9(8), 3100-3111.

35. Estes LM, Singha P, Singh S, Sakthivel TS, Garren M, Devine R, Brisbois EJ, Seal S, Handa H. Characterization of a nitric oxide (NO) donor molecule and cerium oxide nanoparticle (CNP) interactions and their synergistic antimicrobial potential for biomedical applications. Journal of Colloid and Interface Science, 2021; 586:163-177.

34. Garren MR, Ashcraft M, Qian Y, Douglass M, Brisbois EJ, Handa H. Nitric oxide and viral infection: Recent developments in antiviral therapies and platforms. Applied Materials Today 2021; 22:100887.

33.  Devine R, Goudie MG, Singha P, Douglass M, Schmiedt C, Brisbois EJ, Handa H. Mimicking the endothelium: dual action heparinized nitric oxide releasing surface. ACS Applied Materials & Interfaces 2020; 12(18), 20158–20171. 

32. Barnes M, Brisbois EJ. Clinical use of inhaled nitric oxide: local and systemic applications. Free Radical Biology & Medicine 2019; 152:422-31.

31. Chug MK, Feit C, Brisbois EJ. Increasing the lifetime of insulin cannula with antifouling and nitric oxide releasing properties. ACS Applied Bio Materials  2019; 2(12):5965-75. 

30. Feit, CG, Chug, MK, Brisbois, EJ. Development of S-nitroso-N-Acetylpenicillamine impregnated medical grade polyvinyl chloride for antimicrobial medical device interfaces. ACS Applied Biomaterials 2019; 2(10): 4335-4345.

29. Mondal A, Douglass M, Hopkins SP, Singha P, Tran M, Handa H, Brisbois EJ. Multifunctional S-nitroso-N-acetylpenicillamine incorporated medical grade polymer with selenium interface for biomedical applications. ACS Applied Materials & Interfaces 2019; 11: 34652-34662.

28. McCabe MM, Hala P, Rojas-Pena A, Lautner-Csorba O, Major TC, Ren H, Bartlett RH, Brisbois EJ, Meyerhoff ME. Enhancing analytical accuracy of intravascular electrochemical oxygen sensors via nitric oxide release using S-nitroso-N-acetyl-penicillamine (SNAP) impregnated catheter tubing. Talenta 2019; 205: 120077. 

27. Barnes M, Feit C, Grant T, Brisbois EJ.  Antimicrobial polymer modifications to reduce microbial bioburden on endotracheal tubes and ventilator associated pneumonia.  Acta Biomaterialia 2019; 91: 220-34.

26. Lautner G, Stringer B, Brisbois EJ, Meyerhoff ME, Schwendeman SP.  Controlled light-induced gas phase nitric oxide release from S-nitrosothiol-doped silicone rubber films.  Nitric Oxide 2019; 86: 31-7.

25.  Goudie MJ, Singha P, Hopkins SP, Brisbois EJ, Handa H. Active release of an antimicrobial and antiplatelet agent from a non-fouling surface modification.  ACS Applied Materials & Interfaces 2019; 11(4): 4523-30.

24. Major TC, Brisbois EJ, Meyerhoff ME, Bartlett RH. Attenuation of thrombin-induced fibrin formation through changes in fibrinogen conformation induced by reaction with S-nitros-N-acetylpenicillamine, but not S-nitrosoglutathione.   Journal of Materials Chemistry B 2018; 6: 7954-65.

23. Seal S, Singh S, Crawford K, Brisbois EJ, Coathup M.  Novel polymers for use in total joint arthroplasty. Advanced Materials & Processes 2018; 176(7): 30-33.

22. Wo Y, Brisbois EJ, Meyerhoff ME.  Improving the hemocompatibility of intravascular catheters via NO release/generation.  In: Siedlecki C, editor.  Hemocompatibility of biomaterials for clinical applications: blood-biomaterial interactions: Woodhead/Elsevier Publishers 2018; 431-66.

21. Qin Y, Zajda J, Brisbois EJ, Ren H, Toomasian J, Major TC, Rojas-Pena A, Carr B, Johnson T, Haft J, Bartlett RH, Hunt A, Lehnert N, Meyerhoff ME. Portable nitric oxide (NO) generator based on electrochemical reduction of nitrite for potential applications in inhaled NO therapy and cardiopulmonary bypass surgery.  Molecular Pharmaceutics 2017; 14(11): 3762-71.

20.  Pant J, Goudie MJ, Hopkins S, Brisbois EJ, Handa H.  Tunable nitric oxide (NO) release from S-nitroso-N-acetylpenicillamine (SNAP) via catalytic copper nanoparticles for biomedical applications. ACS Applied Materials & Interfaces 2017; 9(18): 15254-64.

19.  Wo Y, Li Z, Colletta A, Wu J, Xi C, Matzger AJ, Brisbois EJ, Bartlett RH, Meyerhoff ME.  Study of crystal formation and nitric oxide (NO) release mechanism from S-nitroso-N-acetylpenicillamine (SNAP)-doped CarboSil polymer composites, a functional biomaterial for potential antimicrobial applications.  Composites Part B: Engineering 2017; 121: 23-33.

18.  Wo Y, Brisbois EJ, Wu J, Li Z, Major TC, Li Z, Mohammed A, Wang X, Colletta A, Bull JL, Matzger AJ, Xi C, Bartlett RH, Meyerhoff ME.  Reduction of thrombosis and bacterial infection via controlled nitric oxide (NO) release from S-nitroso-N-acetylpenicillamine (SNAP) impregnated CarboSil intravascular catheters.  ACS Biomaterials Science & Engineering 2017; 3(3): 349-59.

17.  Brisbois EJ, Kim M, Wang X, Mohammed A, Major TC, Wu J, Brownstein J, Xi C, Handa H, Bartlett RH, Meyerhoff ME.  Improved hemocompatibility of multi-lumen catheters via nitric oxide (NO) release from S-nitroso-N-acetylpenicillamine (SNAP) composite filled lumen. ACS Applied Materials & Interfaces 2016; 8(43): 29270-79.

16.  Brisbois EJ, Major TC, Goudie MJ, Meyerhoff ME, Bartlett RH, Handa H.  Attenuation of thrombosis and bacterial infection using dual function nitric oxide releasing central venous catheters in a 9-day rabbit model. Acta Biomaterialia 2016; 44: 304-12.

15.  Wo Y, Brisbois EJ, Meyerhoff ME.  Recent advances in antithrombotic and antibacterial polymers for biomedical applications:  Just say yes to nitric oxide (NO).  Biomaterials Science 2016; 4(8): 1161-83. (cover feature)

14. Pant J, Goudie MJ, Brisbois EJ, Handa H. Nitric oxide releasing polyurethanes. In: Advances in Polyurethane Biomaterials; Guan G, Cooper SL, editors; Woodhead/Elsevier Publishers 2016; p. 417-438.

13.  Yu J, Brisbois EJ, Handa H, Annich GM, Meyerhoff ME, H, Bartlett RH, Major TC.  The immobilization of a direct thrombin inhibitor to a polyurethane as a nonthrombogenic surface coating for extracorporeal circulation. Journal of Materials Chemistry B 2016; 4(13): 2264-72.

12. Brisbois EJ, Major TC, Goudie MJ, Bartlett RH, Meyerhoff ME, Handa H.  Improved hemocompatibility of silicone rubber extracorporeal tubing via solvent swelling-impregnation of S-nitroso-N-acetylpenicillamine (SNAP) and evaluation in rabbit thrombogenicity model. Acta Biomaterialia 2016; 37: 111-19.

11. Goudie MJ, Brisbois EJ, Pant J, Thompson A, Potkay JA, Handa H. Characterization of an S-nitroso-N-acetylpenicillamine–based nitric oxide releasing polymer from a translational perspective. International Journal of Polymeric Materials and Polymeric Biomaterials 2016; 65(15): 769-78. 

10.  Wo Y, Li Z, Brisbois EJ, Colletta A, Bartlett RH, Matzger AJ, Meyerhoff ME.  Origin of long-term storage stability and nitric oxide release behavior of CarboSil polymer doped with S-nitroso-N-acetyl-D-penicillamine.  ACS Applied Materials & Interfaces 2015; 7(40): 22218–27.

9.  Brisbois EJ, Davis RP, Jones AM, Major TC, Bartlett RH, Meyerhoff ME, Handa H.  Reduction in thrombosis and bacterial adhesion with 7 day implantation of S-nitroso-N-acetylpenicillamine (SNAP)-doped Elast-eon E2As catheters in sheep.  Journal of Materials Chemistry B 2015; 3(8): 1639-45.

8.  Brisbois EJ, Handa H, Meyerhoff ME.  Recent advances in hemocompatible polymers for biomedical applications.  In: Advanced Polymers in Medicine; Puoci F, editor; Springer International Publishing 2015; p. 481-511.

7.  Brisbois EJ, Handa H, Bayliss J, Wu J, Wang S, Xi W, Bartlett RH, Meyerhoff ME.  Optimized polymeric film-based nitric oxide delivery inhibits bacterial growth in a mouse burn wound model.  Acta Biomaterialia 2014; 10(10): 4136-42.

6.  Major TC, Brisbois EJ, Jones AM, Zanetti ME, Annich GM, Bartlett RH, Handa H. The effect of a polyurethane coating incorporating both a thrombin inhibitor and nitric oxide on hemocompatibility in extracorporeal circulation.  Biomaterials 2014; 35(26): 7271-85.

5.  Handa H, Major TC, Brisbois EJ, Bartlett RH; Meyerhoff ME.  Hemocompatibility comparison of biomedical grade polymers using extracorporeal circulation rabbit model of thrombogencity for application in nitric oxide releasing surfaces.  Journal of Materials Chemistry B 2014; 2(8): 1059-67.

4.  Major TC, Handa H, Brisbois EJ, Annich GM, Reynolds MM, Meyerhoff ME, Bartlett RH.  The mediation of platelet quiescence by NO-releasing polymers via cGMP-induced serine 239 phosphorylation of vasodilator-stimulated phosphoprotein.  Biomaterials 2013; 34(33): 8086-96.

3.  Handa H, Brisbois EJ, Major TC, Refahiyat L, Amoako KA, Annich GM, Bartlett RH, Meyerhoff ME. In vitro and in vivo study of sustained nitric oxide release coating using diazeniumdiolate-doped poly(vinyl chloride) matrix with poly(lactic-co-glycolic acid) additives.  Journal of Materials Chemistry B 2013; 1(29): 3578-87.

2.  Brisbois EJ, Handa H, Major TC, Bartlett RH, Meyerhoff ME.  Long-term nitric oxide release and elevated temperature stability with S-nitroso-N-acetylpenicillamine (SNAP)-doped Elast-eon E2As polymer.  Biomaterials 2013; 34(28): 6957-66.

1.  Huang C, Brisbois EJ, Meyerhoff ME.  Flow injection measurements of S-nitrosothiols species in biological samples using amperometric nitric oxide sensor and soluble organoselenium catalyst reagent.  Analytical and Bioananalytical Chemistry 2011; 400(4): 1125-35.