Publications

Google Scholar
  1. Chug MK, Crutchfield N, Garren M, Handa H, Brisbois EJ. Engineering Nitric Oxide-releasing Antimicrobial Dental Coating for Targeted Gingival Therapy. ACS Applied Bio Materials, 2024. In print.
  2. Catori DM, da Silva LCE, de Oliveira MF, Nguyen GH, Moses JC, Brisbois EJ, Handa H, de Oliveira MG. In Situ Photo-crosslinkable Hyaluronic Acid/Gelatin Hydrogel for Local Nitric Oxide Delivery. ACS Applied Materials & Interfaces, 2023; 15, 42, 48930–48944.
  3. Wu Y, Garren MR, Estes Bright LM, Maffe P, Brooks M, Brisbois EJ, Handa H. Enhanced antibacterial efficacy against antibiotic-resistant bacteria via nitric oxide-releasing ampicillin polymer substrates. Journal of Colloid and Interface Science, 2024; 653, Part B, 1763-1774.
  4. Chug MK, Griffin L, Garren M, Tharp E, Nguyen GH, Handa H, Brisbois EJ. Antimicrobial Efficacy of a Nitric Oxide-Releasing Ampicillin Conjugate Catheter Lock Solution on Clinically-Isolated Antibiotic-Resistant Bacteria. Biomaterials Science, 2023; 11, 6561-6572.
  5. Sapkota A, Mondal A, Chug MK, Brisbois EJ. Biomimetic catheter surface with dual action NO releasing and generating properties for enhanced antimicrobial efficacy. Journal of Biomedical Materials Research: Part A, 2023; 1– 15.
  6. Estes Bright LM, Wu Y, Brisbois EJ, Handa H. Advances in Nitric Oxide-Releasing Hydrogels for Biomedical Applications. Current Opinion in Colloid & Interface Science, 2023; 66: 101704.
  7. Mondal A, Maffe P, Wilson SN, Ghalei S, Palacio R, Handa H, Brisbois EJ. Catalytic Effect of Transition Metal-doped Medical Grade Polymer on S-nitrosothiol Decomposition and its Biological Response. Materials Advances. 2023; 4, 3197-206.
  8. Kumar A, Mondal A, Douglass ME, Francis DJ, Garren MR, Estes Bright LM, Ghalei S, Xie J, Brisbois EJ, Handa H. Nanoarchitectonics of Nitric Oxide Releasing Supramolecular Structures for enhanced Antibacterial Efficacy Under Visible Light Irradiation. Journal of Colloid and Interface Surface, 2023; 640: 144-161.
  9. Garren M, Ashcraft M, Crowley D, Brisbois EJ, Handa H. Derivatization of graphene oxide nanosheets with tunable nitric oxide release for antibacterial biomaterials. Journal of Biomedical Materials Research: Part A, 2023; 1-14.
  10. Chug MK, Brisbois EJ. Recent developments in multifunctional antimicrobial surfaces and applications towards advanced nitric oxide based biomaterials. ACS Materials Au, 2022; 2(5): 525-551. (cover feature)
  11. Chug MK, Brisbois EJ. Smartphone compatible nitric oxide releasing insert to prevent catheter-associated infections. Journal of Controlled Release, 2022; 349: 227-240. (cover feature)
  12. Qian Y, Chug MK, Brisbois EJ. Nitric oxide-releasing silicone oil with tunable payload for antibacterial applications. ACS Applied Bio Materials, 2022; 5(7): 3396–3404.
  13. Kumar R, Chug MK, Brisbois EJ. Long-term storage stability and nitric oxide release behavior of (N-acetyl-S-nitrosopenicillaminyl)-S-nitrosopenicillamine (SNAP-SNAP)-incorporated silicone rubber coatings. ACS Applied Materials & Interfaces, 2022; 14(27): 30595–30606.
  14. Qian Y, Chug MK, Massoumi H, Brisbois EJ. S-Nitroso-N-acetylpenicillamine grafted silicone oil for antibacterial interface applications. Material Advances, 2022; 3: 6270-6279.
  15. Massoumi H, Chug MK, Nguyen GH, Brisbois EJ. A multidisciplinary experiment to characterize antifouling biocompatible interfaces via quantification of surface protein adsorption. Journal of Chemical Education, 2022; 99(7): 2667–2676.
  16. Estes LM, Garren MRS, Ashcraft M, Kumar A, Husain H, Brisbois EJ, Handa H. Dual action nitric oxide and fluoride ion-releasing hydrogels for combating dental caries. ACS Applied Materials & Interfaces, 2022; 14(19): 21916-30.
  17. Massoumi H, Kumar R, Chug MK, Qian Y, Brisbois EJ. Nitric oxide release and antibacterial efficacy analyses of S-nitroso-N-acetyl-penicillamine conjugated to titanium dioxide nanoparticles. ACS Applied Bio Materials, 2022; 5(5): 2285–2295.
  18. Chug MK, Massoumi H, Wu Y, Brisbois EJ. Prevention medical device infections via multi-action nitric oxide and chlorhexidine diacetate releasing medical grade silicone biointerfaces. Journal of Biomedical Materials Research: Part A, 2022; 110(6): 1263- 77. (cover feature)
  19. Douglass M, Ghalei S, Brisbois EJ, Handa H. Potent, broad-spectrum antimicrobial effects of S-nitroso-N-acetylpenicillamine-impregnated nitric oxide-releasing latex urinary catheters. ACS Applied Bio Materials, 2022; 5(2): 700–710.
  20. Douglass M, Hopkins S, Chug MK, Kim G, Garren MR, Ashcraft M, Nguyen DT, Tayag N, Handa H, Brisbois EJ. Reduction in foreign body response and improved antimicrobial efficacy via silicone-oil-infused nitric-oxide-releasing medical-grade cannulas. ACS Applied Materials & Interfaces, 2021; 13(44): 52425–52434.
  21. Qian Y, Kumar R, Chug MK, Massoumi H, Brisbois EJ. Therapeutic delivery of nitric oxide utilizing saccharide-based materials. Applied Materials & Interfaces, 2021; 13(44): 52250-52273.
  22. Kumar R, Massoumi H, Chug MK, Brisbois EJ. S-nitroso-N-acetyl-l-cysteine ethyl ester (SNACET) catheter lock solution to reduce catheter-associated infections. ACS Applied Materials & Interfaces, 2021; 13(22): 25813–25824.
  23. Chug MK, Bachtiar E, Gall K, Brisbois EJ. Tailoring nitric oxide release with additive manufacturing to create antimicrobial surfaces. Biomaterials Science, 2021; 9(8): 3100-3111.
  24. Estes LM, Singha P, Singh S, Sakthivel TS, Garren M, Devine R, Brisbois EJ, Seal S, Handa H. Characterization of a nitric oxide (NO) donor molecule and cerium oxide nanoparticle (CNP) interactions and their synergistic antimicrobial potential for biomedical applications. Journal of Colloid and Interface Science, 2021; 586:163-177.
  25. Garren MR, Ashcraft M, Qian Y, Douglass M, Brisbois EJ, Handa H. Nitric oxide and viral infection: Recent developments in antiviral therapies and platforms. Applied Materials Today, 2021; 22: 100887.
  26. Devine R, Goudie MG, Singha P, Douglass M, Schmiedt C, Brisbois EJ, Handa H. Mimicking the endothelium: dual action heparinized nitric oxide releasing surface. ACS Applied Materials & Interfaces, 2020; 12(18): 20158–20171.
  27. Barnes M, Brisbois EJ. Clinical use of inhaled nitric oxide: local and systemic applications. Free Radical Biology & Medicine, 2019; 152:422-31.
  28. Chug MK, Feit C, Brisbois EJ. Increasing the lifetime of insulin cannula with antifouling and nitric oxide releasing properties. ACS Applied Bio Materials, 2019; 2(12): 5965-75.
  29. Feit, CG, Chug, MK, Brisbois, EJ. Development of S-nitroso-N-Acetylpenicillamine impregnated medical grade polyvinyl chloride for antimicrobial medical device interfaces. ACS Applied Biomaterials, 2019; 2(10): 4335-4345.
  30. Mondal A, Douglass M, Hopkins SP, Singha P, Tran M, Handa H, Brisbois EJ. Multifunctional S-nitroso-N-acetylpenicillamine incorporated medical grade polymer with selenium interface for biomedical applications. ACS Applied Materials & Interfaces, 2019; 11: 34652-34662.
  31. McCabe MM, Hala P, Rojas-Pena A, Lautner-Csorba O, Major TC, Ren H, Bartlett RH, Brisbois EJ, Meyerhoff ME. Enhancing analytical accuracy of intravascular electrochemical oxygen sensors via nitric oxide release using S-nitroso-N-acetyl-penicillamine (SNAP) impregnated catheter tubing. Talenta, 2019; 205: 120077.
  32. Barnes M, Feit C, Grant T, Brisbois EJ.  Antimicrobial polymer modifications to reduce microbial bioburden on endotracheal tubes and ventilator associated pneumonia.  Acta Biomaterialia, 2019; 91: 220-34.
  33. Lautner G, Stringer B, Brisbois EJ, Meyerhoff ME, Schwendeman SP.  Controlled light-induced gas phase nitric oxide release from S-nitrosothiol-doped silicone rubber films.  Nitric Oxide, 2019; 86: 31-7.
  34. Goudie MJ, Singha P, Hopkins SP, Brisbois EJ, Handa H. Active release of an antimicrobial and antiplatelet agent from a non-fouling surface modification.  ACS Applied Materials & Interfaces, 2019; 11(4): 4523-30.
  35. Major TC, Brisbois EJ, Meyerhoff ME, Bartlett RH. Attenuation of thrombin-induced fibrin formation through changes in fibrinogen conformation induced by reaction with S-nitros-N-acetylpenicillamine, but not S-nitrosoglutathione.   Journal of Materials Chemistry B, 2018; 6: 7954-65.
  36. Seal S, Singh S, Crawford K, Brisbois EJ, Coathup M.  Novel polymers for use in total joint arthroplasty. Advanced Materials & Processes, 2018; 176(7): 30-33.
  37. Wo Y, Brisbois EJ, Meyerhoff ME.  Improving the hemocompatibility of intravascular catheters via NO release/generation.  In: Siedlecki C, editor.  Hemocompatibility of biomaterials for clinical applications: blood-biomaterial interactions: Woodhead/Elsevier Publishers 2018; 431-66.
  38. Qin Y, Zajda J, Brisbois EJ, Ren H, Toomasian J, Major TC, Rojas-Pena A, Carr B, Johnson T, Haft J, Bartlett RH, Hunt A, Lehnert N, Meyerhoff ME. Portable nitric oxide (NO) generator based on electrochemical reduction of nitrite for potential applications in inhaled NO therapy and cardiopulmonary bypass surgery.  Molecular Pharmaceutics, 2017; 14(11): 3762-71.
  39. Pant J, Goudie MJ, Hopkins S, Brisbois EJ, Handa H.  Tunable nitric oxide (NO) release from S-nitroso-N-acetylpenicillamine (SNAP) via catalytic copper nanoparticles for biomedical applications. ACS Applied Materials & Interfaces, 2017; 9(18): 15254-64.
  40. Wo Y, Li Z, Colletta A, Wu J, Xi C, Matzger AJ, Brisbois EJ, Bartlett RH, Meyerhoff ME.  Study of crystal formation and nitric oxide (NO) release mechanism from S-nitroso-N-acetylpenicillamine (SNAP)-doped CarboSil polymer composites, a functional biomaterial for potential antimicrobial applications.  Composites Part B: Engineering, 2017; 121: 23-33.
  41. Wo Y, Brisbois EJ, Wu J, Li Z, Major TC, Li Z, Mohammed A, Wang X, Colletta A, Bull JL, Matzger AJ, Xi C, Bartlett RH, Meyerhoff ME.  Reduction of thrombosis and bacterial infection via controlled nitric oxide (NO) release from S-nitroso-N-acetylpenicillamine (SNAP) impregnated CarboSil intravascular catheters.  ACS Biomaterials Science & Engineering, 2017; 3(3): 349-59.
  42. Brisbois EJ, Kim M, Wang X, Mohammed A, Major TC, Wu J, Brownstein J, Xi C, Handa H, Bartlett RH, Meyerhoff ME.  Improved hemocompatibility of multi-lumen catheters via nitric oxide (NO) release from S-nitroso-N-acetylpenicillamine (SNAP) composite filled lumen. ACS Applied Materials & Interfaces, 2016; 8(43): 29270-79.
  43. Brisbois EJ, Major TC, Goudie MJ, Meyerhoff ME, Bartlett RH, Handa H.  Attenuation of thrombosis and bacterial infection using dual function nitric oxide releasing central venous catheters in a 9-day rabbit model. Acta Biomaterialia, 2016; 44: 304-12.
  44. Wo Y, Brisbois EJ, Meyerhoff ME.  Recent advances in antithrombotic and antibacterial polymers for biomedical applications:  Just say yes to nitric oxide (NO).  Biomaterials Science, 2016; 4(8): 1161-83. (cover feature)
  45. Pant J, Goudie MJ, Brisbois EJ, Handa H. Nitric oxide releasing polyurethanes. In: Advances in Polyurethane Biomaterials; Guan G, Cooper SL, editors; Woodhead/Elsevier Publishers 2016; p. 417-438.
  46. Yu J, Brisbois EJ, Handa H, Annich GM, Meyerhoff ME, H, Bartlett RH, Major TC.  The immobilization of a direct thrombin inhibitor to a polyurethane as a nonthrombogenic surface coating for extracorporeal circulation. Journal of Materials Chemistry B, 2016; 4(13): 2264-72.
  47. Brisbois EJ, Major TC, Goudie MJ, Bartlett RH, Meyerhoff ME, Handa H.  Improved hemocompatibility of silicone rubber extracorporeal tubing via solvent swelling-impregnation of S-nitroso-N-acetylpenicillamine (SNAP) and evaluation in rabbit thrombogenicity model. Acta Biomaterialia, 2016; 37: 111-19.
  48. Goudie MJ, Brisbois EJ, Pant J, Thompson A, Potkay JA, Handa H. Characterization of an S-nitroso-N-acetylpenicillamine–based nitric oxide releasing polymer from a translational perspective. International Journal of Polymeric Materials and Polymeric Biomaterials, 2016; 65(15): 769-78.
  49. Wo Y, Li Z, Brisbois EJ, Colletta A, Bartlett RH, Matzger AJ, Meyerhoff ME.  Origin of long-term storage stability and nitric oxide release behavior of CarboSil polymer doped with S-nitroso-N-acetyl-D-penicillamine.  ACS Applied Materials & Interfaces, 2015; 7(40): 22218–27.
  50. Brisbois EJ, Davis RP, Jones AM, Major TC, Bartlett RH, Meyerhoff ME, Handa H.  Reduction in thrombosis and bacterial adhesion with 7 day implantation of S-nitroso-N-acetylpenicillamine (SNAP)-doped Elast-eon E2As catheters in sheep.  Journal of Materials Chemistry B, 2015; 3(8): 1639-45.
  51. Brisbois EJ, Handa H, Meyerhoff ME.  Recent advances in hemocompatible polymers for biomedical applications.  In: Advanced Polymers in Medicine; Puoci F, editor; Springer International Publishing 2015; p. 481-511.
  52. Brisbois EJ, Handa H, Bayliss J, Wu J, Wang S, Xi W, Bartlett RH, Meyerhoff ME.  Optimized polymeric film-based nitric oxide delivery inhibits bacterial growth in a mouse burn wound model.  Acta Biomaterialia, 2014; 10(10): 4136-42.
  53. Major TC, Brisbois EJ, Jones AM, Zanetti ME, Annich GM, Bartlett RH, Handa H. The effect of a polyurethane coating incorporating both a thrombin inhibitor and nitric oxide on hemocompatibility in extracorporeal circulation.  Biomaterials, 2014; 35(26): 7271-85.
  54. Handa H, Major TC, Brisbois EJ, Bartlett RH; Meyerhoff ME.  Hemocompatibility comparison of biomedical grade polymers using extracorporeal circulation rabbit model of thrombogencity for application in nitric oxide releasing surfaces.  Journal of Materials Chemistry B, 2014; 2(8): 1059-67.
  55. Major TC, Handa H, Brisbois EJ, Annich GM, Reynolds MM, Meyerhoff ME, Bartlett RH.  The mediation of platelet quiescence by NO-releasing polymers via cGMP-induced serine 239 phosphorylation of vasodilator-stimulated phosphoprotein.  Biomaterials, 2013; 34(33): 8086-96.
  56. Handa H, Brisbois EJ, Major TC, Refahiyat L, Amoako KA, Annich GM, Bartlett RH, Meyerhoff ME. In vitro and in vivo study of sustained nitric oxide release coating using diazeniumdiolate-doped poly(vinyl chloride) matrix with poly(lactic-co-glycolic acid) additives.  Journal of Materials Chemistry B, 2013; 1(29): 3578-87.
  57. Brisbois EJ, Handa H, Major TC, Bartlett RH, Meyerhoff ME.  Long-term nitric oxide release and elevated temperature stability with S-nitroso-N-acetylpenicillamine (SNAP)-doped Elast-eon E2As polymer.  Biomaterials, 2013; 34(28): 6957-66.
  58. Huang C, Brisbois EJ, Meyerhoff ME.  Flow injection measurements of S-nitrosothiols species in biological samples using amperometric nitric oxide sensor and soluble organoselenium catalyst reagent.  Analytical and Bioananalytical Chemistry, 2011; 400(4): 1125-35.